Whipple Pancreaticoduodenectomy

CPT 48150
Approach Open
Add-on / Variant CPTs
  • 48153 — Proximal subtotal pancreatectomy without duodenectomy
  • 48154 — Pancreatectomy with total duodenectomy
  • 48155 — Distal pancreatectomy with duodenectomy

Pancreatic head carcinoma / periampullary carcinoma / ampullary adenoma / chronic pancreatitis / distal cholangiocarcinoma

Same

Pylorus-preserving pancreaticoduodenectomy (Whipple procedure)

[Attending name], MD/DO

[Resident/PA name]

General endotracheal

The patient is a [age]-year-old [male/female] with [pancreatic head / periampullary / ampullary] [carcinoma/mass] presenting for resection. Preoperative staging demonstrated [cT_N_M_]. The tumor was deemed [resectable/borderline resectable] on cross-sectional imaging without evidence of [SMA/SMV/portal vein] involvement precluding resection. [Neoadjuvant therapy was/was not completed.] The risks, benefits, and alternatives were discussed with the patient, and informed consent was obtained.

A [mass/tumor] was palpable in the [pancreatic head/ampulla/distal bile duct]. The superior mesenteric vein (SMV) and portal vein were [patent and uninvolved / with [< 180 degree] abutment requiring [vein resection/patch repair]]. The superior mesenteric artery was [uninvolved] with a [clear/narrow] fat plane. The hepatic artery was [normal / with replaced right hepatic artery from the SMA, which was preserved]. No evidence of peritoneal or hepatic metastases. [Additional findings or none].

The patient was brought to the operating room and placed supine. General endotracheal anesthesia was induced. Foley catheter and nasogastric tube were placed. A surgical timeout was performed confirming patient identity, procedure, operative site, allergies, and administration of prophylactic antibiotics.

The abdomen was prepped and draped in sterile fashion. An upper midline laparotomy was performed. Abdominal exploration confirmed resectability — no peritoneal deposits, no hepatic metastases, and no vascular involvement precluding resection. A self-retaining retractor was placed.

The hepatoduodenal ligament was dissected. The common bile duct was encircled. A cholecystectomy was performed. The common hepatic duct was divided just above the cystic duct insertion. The gastroduodenal artery was identified, ligated with [2-0 silk / hem-o-lok], and divided at its origin from the proper hepatic artery.

The duodenum was mobilized via an extended Kocher maneuver sweeping the duodenum and pancreatic head off the retroperitoneum and inferior vena cava. The SMV was identified below the neck of the pancreas. A tunnel was developed between the posterior surface of the pancreatic neck and the anterior surface of the SMV/portal vein confluence.

The stomach was divided just proximal to the pylorus (classic technique) [or the pylorus was preserved and the duodenum divided 1-2 cm distal to the pylorus (pylorus-preserving technique)] using a GIA stapler. The jejunum was divided approximately 10-15 cm distal to the ligament of Treitz with a GIA stapler. The proximal jejunum was passed under the superior mesenteric vessels to the right. The uncinate process was dissected off the superior mesenteric artery (SMA), dividing the pancreatic head/uncinate tributaries with [hem-o-lok clips/ties]. The pancreatic neck was divided over the SMV using [electrocautery/scalpel], and a [3-0 Prolene] stitch was placed in the main pancreatic duct for identification. The specimen was removed.

Reconstruction was performed in a retrocolic or antecolic Roux-en-Y fashion with the jejunum brought through a defect in the transverse mesocolon. The pancreatic anastomosis (pancreaticojejunostomy, [duct-to-mucosa / invagination technique]) was constructed first with an interrupted outer layer of [3-0 silk] and a duct-to-mucosa inner layer of [4-0 PDS] over a [5-Fr pancreatic duct stent]. The hepaticojejunostomy was constructed as a single-layer end-to-side anastomosis with [4-0 PDS] interrupted sutures. The duodenojejunostomy (or gastrojejunostomy) was constructed as a two-layer end-to-side anastomosis [___] cm distal to the hepaticojejunostomy.

The abdomen was irrigated. Hemostasis was confirmed. Two closed suction drains were placed adjacent to the pancreatic anastomosis and hepaticojejunostomy. The nasogastric tube was repositioned. The fascia was closed with running [#1 PDS]. Skin was closed with [staples]. Sterile dressings were applied.

None

Pancreaticoduodenectomy specimen (pancreatic head, duodenum, proximal jejunum, gallbladder, distal common bile duct) sent to pathology for margin analysis

[___] mL

Two [Jackson-Pratt] drains placed adjacent to the pancreatic anastomosis and hepaticojejunostomy, brought out through separate stab incisions

The patient tolerated the procedure well and was taken to the post-anesthesia care unit in stable condition.

Epic SmartPhrase Version
PREOPERATIVE DIAGNOSIS: ***
POSTOPERATIVE DIAGNOSIS: Same
PROCEDURE PERFORMED: Pylorus-preserving pancreaticoduodenectomy (Whipple)
ATTENDING SURGEON: ***, MD/DO
FIRST ASSISTANT: ***
ANESTHESIA: General endotracheal

INDICATIONS: The patient is a .PTAGE-year-old .PTSEX with *** pancreatic head/periampullary mass. Resectable on imaging. *** neoadjuvant therapy. Informed consent obtained.

FINDINGS: Mass in the ***. SMV/portal vein ***. SMA ***. Hepatic artery ***. No metastatic disease.

DESCRIPTION OF PROCEDURE:
Supine position. Foley, NGT. General anesthesia. Surgical timeout per protocol.

Upper midline laparotomy. Abdominal exploration confirmed resectability. Cholecystectomy performed. CBD divided above cystic duct. GDA ligated and divided. Extended Kocher maneuver. Tunnel developed between pancreatic neck and SMV. Pylorus-preserving duodenal division 1-2 cm distal to pylorus. Jejunum divided 10-15 cm past ligament of Treitz. Uncinate dissected off SMA. Pancreatic neck divided over SMV; main duct identified. Specimen removed.

Retrocolic reconstruction: pancreaticojejunostomy (duct-to-mucosa with *** stent), hepaticojejunostomy (single-layer end-to-side), duodenojejunostomy (two-layer). Two JP drains placed.

Fascia closed with #1 PDS. Skin closed with staples.

ESTIMATED BLOOD LOSS: ***
SPECIMENS: Pancreaticoduodenectomy specimen to pathology
COMPLICATIONS: None
DRAINS: Two JP drains adjacent to anastomoses
DISPOSITION: The patient tolerated the procedure well and was taken to the post-anesthesia care unit in stable condition.

Signed: .ME, .MYDEGREE
.TODAY
Variants

Classic Whipple (Antrectomy)

The classic Whipple technique was used with distal gastrectomy (antrectomy) rather than pylorus preservation. The stomach was divided approximately 30-40% from the pylorus using a GIA stapler, removing the distal stomach with the specimen. Reconstruction included a gastrojejunostomy (Billroth II configuration) in place of a duodenojejunostomy.

With Portal/SMV Vein Resection

Intraoperative assessment revealed [< 180 degree / segmental] involvement of the [SMV/portal vein]. Systemic heparin was administered ([5000 units IV]). The involved segment was resected and [primary end-to-end venorrhaphy / interposition graft with [internal jugular / left renal vein / PTFE graft]] was performed. Flow was confirmed after repair.

With Replaced/Accessory Right Hepatic Artery

A replaced right hepatic artery arising from the SMA was identified in the hepatoduodenal ligament. This vessel was carefully preserved throughout the dissection. The uncinate process was dissected off the SMA medial to the replaced right hepatic artery, taking care to protect its origin.

Charting Tips
  • Document the drain amylase level orders — POD1 and POD3 drain amylase levels are required per ISGPF criteria for diagnosing postoperative pancreatic fistula (POPF). Many institutions require this but a note in the operative record ensuring drain placement proximity to the PJ anastomosis is important.
  • Replaced or accessory hepatic artery identification and preservation must be documented — this occurs in approximately 20% of Whipple patients and is the most feared vascular injury. If identified, note which vessel and that it was preserved.
  • Document the pancreatic texture (soft/firm) and duct size — these two factors (soft gland + small duct < 3 mm) define the highest-risk group for POPF and should be in the note to frame subsequent clinical decision-making.
Billing Tips
  • Bill 48150 for pancreaticoduodenectomy with pancreatojejunostomy (Whipple, 50.73 wRVU, 90-day global). Bill 48152 for Whipple without pancreatojejunostomy (pancreatic duct ligation or drainage, 52.32 wRVU).
  • Bill 48153 for pylorus-sparing pancreaticoduodenectomy (48.88 wRVU). Bill 48154 for pylorus-sparing without pancreatojejunostomy (49.28 wRVU). Document pylorus preservation or resection explicitly — code selection depends on this.
  • Vascular resection and reconstruction (SMV/portal vein) is not a separately listed code for Whipple — modifier -22 (increased complexity) is appropriate when vascular resection is required. Document vessel involvement, resection technique, and reconstruction method.
  • 90-day global period: drain management, pancreatic fistula grading (ISGPF classification), delayed gastric emptying management, and routine follow-up are all bundled. Document complications using standard grading systems for quality reporting.
  • Laparoscopic Whipple uses the same codes (48150-48154) — approach does not change the CPT. Robotic-assisted surgery is also captured by the same codes. Document minimally invasive approach in the operative note.